Size : 5mg
Synonyms: PG(16:0/0:0) sodium, 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) sodium, 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) sodium, 16:0 Lyso PG sodium
| Description | LysoFos Glycerol 16 is a high-purity, mild hemolytic phospholipid detergent with good amphiphilic properties. It promotes the extraction, solubilization, and stabilization of membrane proteins while preserving their native conformation and activity. It is used in the separation and purification of integral membrane proteins, as well as in structural biology and functional studies of membrane proteins. |
| In vivo | Method: Female BALB/c nu/nu mice were subcutaneously inoculated with U-87 MG cells (1×10⁸ cells/mL). Tubulin inhibitor 30 (25 mg/kg) or normal saline was intraperitoneally administered every 2 days for 40 days. Tumor tissues were collected, weighed, and measured for volume. Result: Tumor volume and weight in the Tubulin inhibitor 30-treated group were significantly smaller than those in the normal saline control group[1]. |
| Synonyms | PG(16:0/0:0) sodium, 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) sodium, 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) sodium, 16:0 Lyso PG sodium |
| Molecular Weight | 506.55 |
| Formula | C22H44NaO9P |
| Cas No. | 326495-22-1 |
| Smiles | [Na+].CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC(O)CO |
| Storage | Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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