Description
StemBeads Activin A is a patented growth factor supplement that offers a novel way to culture Activin A dependent cultures more efficiently, with greater control and fewer medium changes. Activin-A can be use to maintain pluripotent stem cells as well differentiate them to different lineages such as endoderm. StemBeads Activin A are microbeads composed of FDA approved, biodegradable PLGA polymer that is loaded with recombinant human Activin A. Under the microscope, StemBeads will appear as small dark spheres. Over time, they break down while releasing the encapsulated protein at a controlled rate. Controlled delivery and stable levels of Activin A improve cell cultures while saving researchers valuable time and resources.
Product Information Sheet
Frequently Asked Questions
SDS – StemBeads® Activin A
Sustained Release Protein Cell Culture
StemBeads are a revolutionary controlled-release growth factor technology. The StemBeads product is currently used for improved cell culture in more than 100 scientific laboratories globally. StemBeads technology encapsulates a growth factor in a PLGA hydrogel that stabilizes the protein and releases it steadily over several days. With growth factor levels stabilized, spontaneous differentiation is reduced, pluripotency is increased, and feeding schedules are reduced to only 2-3 times per week.
StemBeads are added to your medium to achieve a desired growth factor release, sustained over several days. Following, the beads are washed from the culture, the medium is replaced, and the process repeated as required.