Synaptophysin (SYP) Mouse Monoclonal Antibody [Clone ID: 171B5]
CAT#: AM26445AF-N
Synaptophysin (SYP) mouse monoclonal antibody, clone 171B5, Azide Free
Specifications
Product Data | |
Clone Name | 171B5 |
Applications | IHC, WB |
Recommended Dilution | Western blot: 1 μg/ml for chemiluminescence detection system. |
Reactivities | Human, Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified synaptic vesicle fraction from guinea pig cerebrum |
Specificity | Reacts with human and mouse Synaptophysin. |
Formulation | PBS containing 50% glycerol, pH 7.2. Contains no preservtives. State: Azide Free State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A agarose |
Conjugation | Unconjugated |
Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | synaptophysin |
Database Link | |
Background | Synaptophysin (also referred to as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and is reported to be a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins to bind to synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle. |
Synonyms | Neuroendocrine Marker |
Note | This product was originally produced by MBL International. Protocol: SDS-PAGE & Western Blotting Immunohistochemical staining for paraffin-embedded sections: SAB method |
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