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Related reagents - Detection of cell contamination

Related reagents - Detection of cell contamination


Mycoplasma and bacterial contamination is a major concern for research laboratories (e.g. in cell biology) or biopharmaceutical laboratories (production of vaccines, monoclonal antibodies, etc.).

Mycoplasmas are the smallest self-producing microorganisms and can reproduce in extracellular space. Although they are mostly harmless to humans, other host animals and plants, some species can cause disease in humans. In particular, 6 species are a frequent cause of contamination in continuous cell lines and primary cells. Because of their size, mycoplasma are not detectable (e.g. under the microscope) and yet they profoundly alter cell cultures (metabolism, cell growth, pH, viability, membrane transport).
The main source of mycoplasma contamination is other infected cell cultures as well as culture media, reagents (fetal bovine serum, trypsin, etc.) and laboratory personnel.
Mycoplasma contaminations can cost money, time and reputation, compromise research results or impact the safety of biologic therapies. Effective strategies against mycoplasma contaminations are prevention, early detection, removal of infected material, or disposal of mycoplasma.

Early detection of bacteria in cell cultures is the only reasonable solution and the only control measure against a common problem for life science laboratories: bacterial contaminations in cell cultures.
Up to 5% of all cell cultures are contaminated with bacteria but show no visual signs of bacterial contamination, such as turbidity, sudden change in the colour of the medium (phenol red) or microscopic particles. In addition, bacteria may show resistance or lack of sensitivity to standard antibiotics (e.g. penicillin/streptomycin) and have a direct impact on cell metabolism, growth and differentiation.

Cat#
Descrizione
Formato
Prezzo IVA escl.
MBS020196-48
 48-Strip-Wells 
MBS011639-96
 96-Strip-Wells 
MBS265363-48
 48-Strip-Wells 
MBS106267-48
 48-Strip-Wells 
MBS703547-10x96
 10x96-Strip-Wells 
MBS108823-96
 96-Strip-Wells 
MBS2019883-96
 96-Strip-Wells 
MBS2023219-96
 96-Strip-Wells 
MBS020196-96
 96-Strip-Wells 
MBS265363-96
 96-Strip-Wells 
MBS2023723-48
 48-Strip-Wells 
MBS106267-96
 96-Strip-Wells 
MBS045087-48
 48-Strip-Wells 
MBS075109-48
 48-Strip-Wells 
MBS021285-48
 48-Strip-Wells 
MBS2018844-48
 48-Strip-Wells 
MBS2019618-48
 48-Strip-Wells 
MBS045087-96
 96-Strip-Wells 
MBS726665-48-C
 48-Strip-Wells-(Competitive) 
MBS7201754-48
 48-Strip-Wells 
MBS075109-96
 96-Strip-Wells 
MBS021285-96
 96-Strip-Wells 
MBS2604629-96
 96-Strip-Wells 
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