Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare
 
> β-1,3-Glucan [9051-97-2]

β-1,3-Glucan [9051-97-2]

Stampa Stampa
Entra

Cat# orb2941193-100mg

Size : 100mg

Marca : Biorbyt


β-1,3-Glucan

SKU: orb2941193

Description

β-1,3-Glucan is a major constituent of all characterized fungal cell walls, comprising 30% to 80% of wall mass, and β-1,3-Glucan exists as a branched polymer in the cell wall, with branches connected via β-1,6 linkages, enabling investigation into fungal structural biology, cell wall assembly, immunomodulation, and antifungal therapeutic targeting.

Images & Validation

−
β-1,3-Glucan

Key Properties

−
CAS Number9051-97-2
TargetOthers
SolubilityDMSO:4 mg/mL;H2O:30 mg/mL

Bioactivity

−
In Vivo
Adding 0.09% β-1,3-Glucan to feed and administering it orally twice daily for 8 consecutive weeks can effectively promote the growth and development of Larimichthys crocea, enhance its innate immune function, and improve its resistance to Vibrio harveyi infection . Administering β-1,3-Glucan either orally (20 mg/kg/day for 14 consecutive days) or via subcutaneous injection (2 mg/kg/day for 3 consecutive days) can promote blood pressure recovery in a rat endotoxemia model, alleviate liver and kidney function damage in the model animals, and regulate cytokine levels in vivo . For a rat sepsis model induced by cecal ligation and puncture (CLP), intramuscular injection of 2 mg/kg β-1,3-Glucan immediately after surgery and again 4 hours post-surgery can significantly improve the survival rate of the model rats, alleviate acute lung injury symptoms, and inhibit the release of pro-inflammatory cytokines . Administering 150 mg/kg β-1,3-glucan orally once daily for 7 consecutive days to adult male Balb/c mice can reverse the immunosuppressive state induced by Aflatoxin B1, increase the proportion of lymphocyte subsets, and elevate the expression levels of multiple cytokines .
In Vitro
β-1,3-Glucan (0.5-5 mg/mL, 3 days) significantly promotes the proliferation of L-929 fibroblast cells .

Storage & Handling

−
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

−
β Glucan, beta-Glucan
−
  • Poacic acid

    Poacic acid [orb2565455]

    160097-32-5

    342.34

    C19H18O6

    50 mg, 10 mg
  • Curdlan

    Curdlan [orb1303211]

    98.39% (May vary between batches)

    54724-00-4

    209.242

    (C6H10O5)n

  • Pneumocandin B0

    Pneumocandin B0 [orb1301475]

    99.23% (May vary between batches)

    135575-42-7

    1065.21

    C50H80N8O17

    25 mg, 50 mg, 100 mg, 500 mg, 1 ml x 10 mM (in DMSO), 200 mg
  • MK-5204

    MK-5204 [orb1984857]

    1207751-75-4

    695.99

    C40H65N5O5

    5 mg
  • Laminaran

    Laminaran [orb1707102]

    98.00% (May vary between batches)

    9008-22-4

    504.438

    C18H32O16

    500 mg, 100 mg

Quick Database Links

Gene Symbol
Others

Protocol Information