Amitriptyline HCl [549-18-8]
Cat# B2231-1g
Size : 1g
Marca : APExBIO Technology
Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
- 1. Ya Zhang, Lin Liu, et al. "Lipidomics reveals the pro-viral roles of ceramides during fish nodavirus infection." J Virol. 2026 Mar 24;100(3):e0199125. PMID: 41728937
- 2. Juanwen Hu, Xue Jiang, et al. "A surrogate barrier model for high-throughput blood-brain barrier permeability prediction: integrating LLC-PK1-MOCK/MDR1 Cells and lysosomal trapping correction." Drug Deliv. 2025 Dec 31;32(1):2585612. PMID: 41307200
| Storage | Store at -20°C |
| M.Wt | 313.86 |
| Cas No. | 549-18-8 |
| Formula | C20H23N·HCl |
| Solubility | ≥15.69 mg/mL in DMSO; ≥43.9 mg/mL in H2O; ≥50 mg/mL in EtOH |
| Chemical Name | 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride |
| Canonical SMILES | CN(C)CCC=C(c1c(CC2)cccc1)c1c2cccc1.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
