Anti-GPR179 antibody

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC-P 1:50-300 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	GPR179
Gene ID:	440435
Uniprot ID:	GP179_HUMAN
Specificity:	GP179 Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from part of the human protein

Function	Orphan receptor involved in vision. Required for signal transduction through retinal depolarizing bipolar cells. Acts as an atypical G-protein coupled receptor that recruits and regulates the R7 group RGS-GNB5 complexes instead of activating G proteins: promotes the GTPase activator activity of R7 RGS proteins, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Associates with components of metabotropic signaling cascade in retina ON-bipolar neurons, such as TRPM1 and GRM6: may control the ability of the GRM6 cascade to gate TRPM1.
Protein Name	Probable G-Protein Coupled Receptor 179 Probable G-Protein Coupled Receptor 158-Like 1 Gpr158-Like
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Postsynaptic Cell Membrane Cell Projection Dendrite Specifically Localizes To The Tips Of Retinal On-Bipolar Dendrites
Alternative Antibody Names	Anti-Probable G-Protein Coupled Receptor 179 antibody Anti-Probable G-Protein Coupled Receptor 158-Like 1 antibody Anti-Gpr158-Like antibody Anti-GPR179 antibody Anti-GPR158L antibody Anti-GPR158L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance