General Information
| Short Description | Rabbit polyclonal anti-Protein Wnt-2 (200-280 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 200-280 |
| Immunogen Region | 200-280 aa |
| Specificity | WNT2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons. |
| Protein Name | Protein Wnt-2Int-1-Like Protein 1Int-1-Related ProteinIrp |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-2 antibodyAnti-Int-1-Like Protein 1 antibodyAnti-Int-1-Related Protein antibodyAnti-Irp antibodyAnti-WNT2 antibodyAnti-INT1L1 antibodyAnti-IRP antibody |
Information sourced from Uniprot.org