Human TNF-beta

Tumor necrosis factor beta (TNF beta) is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells. TNF beta is also a mediator of inflammation and immune functions. Recombinant TNF beta comprises a 171 amino acid fragment (35-205) corresponding to the mature TNF beta chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag.Tumor necrosis factor beta (TNF beta) is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells. TNF beta is also a mediator of inflammation and immune functions. Recombinant TNF beta comprises a 171 amino acid fragment (35-205) corresponding to the mature TNF beta chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag.