Clinisciences > NFKB1 antibody - N-terminal region
NFKB1 antibody - N-terminal region
Cat# ARP38413_P050
Size : 100ul
Marca : Aviva Systems Biology
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NFKB1 Antibody - N-terminal region (ARP38413_P050)
| Datasheets/Manuals | Printable datasheet for anti-NFKB1 (ARP38413_P050) antibody |
|---|
| Tested Species Reactivity | Human, Chicken |
|---|---|
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish, Chicken |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human NFKB1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86% |
| Peptide Sequence | Synthetic peptide located within the following region: PEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-NFKB1 (ARP38413_P050) antibody is Catalog # AAP38413 (Previous Catalog # AAPP20603) |
| Reference | Heinemann,S., et al., (2006) J. Biol. Chem. 281 (13), 8565-8572 |
|---|---|
| Gene Symbol | NFKB1 |
| Gene Full Name | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Alias Symbols | KBF1, EBP-1, NF-kB, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B1, NF-kappabeta |
| NCBI Gene Id | 4790 |
| Protein Name | Nuclear factor NF-kappa-B p105 subunit |
| Description of Target | NFKB1 is a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B |
| Uniprot ID | P19838 |
| Protein Accession # | NP_003989 |
| Nucleotide Accession # | NM_003998 |
| Protein Size (# AA) | 969 |
| Molecular Weight | 105kDa |
| Protein Interactions | FBXW11; UBC; RELB; RELA; REL; NFKB2; HDAC1; BCL3; NFKB1; RPS3; HIF1AN; NFKBIA; MPP6; PELP1; PLD3; MXD3; IKBKG; RL2; TP63; SRF; MAP3K8; PML; SERPINA3; SPPL2A; TNIP2; NFKBIZ; COPS5; YWHAQ; RGS14; NR4A1; GLUL; ABCC2; TNIP1; COPB2; YY1; PARP1; RPS6KA5; BTRC; |
Protein interactions
| Name | # of Products |
|---|---|
| ANXA4 | 12 |
| BANP | 13 |
| BCL3 | 87 |
| BRMS1 | 28 |
| BTRC | 289 |
| CARM1 | 120 |
| CDK9 | 249 |
| CLU | 87 |
| DPF2 | 62 |
| EP300 | 986 |
| FBXW1 | 12 |
| Gag-pol | 49 |
| HDAC1 | 928 |
| HDAC2 | 549 |
| HDAC3 | 422 |
| HDAC4 | 233 |
| HDAC5 | 906 |
| HMGA1 | 91 |
| ITGB3BP | 63 |
| MEN1 | 81 |
| MTPN | 21 |
| NCOA3 | 285 |
| NCOR2 | 298 |
| NFKBIA | 240 |
| NFKBIZ | 30 |
| NR3C1 | 215 |
| PARP1 | 255 |
| PCBD1 | 87 |
| PDCD11 | 11 |
| POLR2A | 376 |
| PPME1 | 15 |
| PSMD10 | 48 |
| RELA | 381 |
| RPS3 | 57 |
| RSF1 | 16 |
| SF1 | 69 |
| SP1 | 551 |
| SPAG9 | 33 |
| SUMO1 | 972 |
| Tat | 632 |
| TNIP2 | 34 |
| UNC5CL | 10 |
| ZBTB9 | 49 |
| ZFP36 | 30 |
Biological process
| Name | # of Products |
|---|---|
| Anti-apoptosis | 239 |
| Apoptotic process | 586 |
| Cellular response to interleukin-1 | 32 |
| Cellular response to mechanical stimulus | 62 |
| Inflammatory response | 339 |
| Innate immune response | 300 |
| Membrane protein intracellular domain proteolysis | 12 |
| MyD88-dependent toll-like receptor signaling pathway | 65 |
| MyD88-independent toll-like receptor signaling pathway | 56 |
| Negative regulation of calcidiol 1-monooxygenase activity | 3 |
| Negative regulation of cellular protein metabolic process | 5 |
| Negative regulation of cholesterol transport | 4 |
| Negative regulation of transcription from RNA polymerase II promoter | 574 |
| Negative regulation of vitamin D biosynthetic process | 4 |
| Nerve growth factor receptor signaling pathway | 173 |
| Positive regulation of canonical Wnt receptor signaling pathway | 50 |
| Positive regulation of lipid storage | 5 |
| Positive regulation of macrophage derived foam cell differentiation | 24 |
| Positive regulation of NF-kappaB transcription factor activity | 135 |
| Positive regulation of transcription, DNA-dependent | 681 |
| Signal transduction | 1058 |
| T cell receptor signaling pathway | 90 |
| Toll signaling pathway | 66 |
| Toll-like receptor 1 signaling pathway | 59 |
| Toll-like receptor 2 signaling pathway | 61 |
| Toll-like receptor 3 signaling pathway | 54 |
| Toll-like receptor 4 signaling pathway | 64 |
| Toll-like receptor signaling pathway | 71 |
| Transcription from RNA polymerase II promoter | 302 |
| TRIF-dependent toll-like receptor signaling pathway | 53 |
Cellular components
| Name | # of Products |
|---|---|
| Cytoplasm | 4549 |
| Cytosol | 1868 |
| I-kappaB/NF-kappaB complex | 2 |
| Mitochondrion | 1154 |
| Nucleolus | 1179 |
| Nucleoplasm | 775 |
| Nucleus | 4914 |
Protein function
| Name | # of Products |
|---|---|
| Enzyme binding | 898 |
| Nucleic acid binding transcription factor activity | 27 |
| Protein binding | 12191 |
| Regulatory region DNA binding | 77 |
| Sequence-specific DNA binding transcription factor activity | 2776 |
| Transcription regulatory region DNA binding | 657 |
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NFKB1 ELISA Kit (Mouse) : 96 Wells (OKEH01301)Catalog #: OKEH01301Application: ELISA-SandwichKit Range: 0.156-10ng/mLSensitivity: 0.091 ng/mL -
NFKB1 ELISA Kit (Human) (OKEH04591)Catalog #: OKEH04591Application: ELISA-SandwichKit Range: 0.312-20ng/mLSensitivity: 0.23 ng/mL


