Angiopoietin

The angiopoietins are the secreted ligands of the Tie family of protein receptor tyrosine kinases. Angiopoietin 2 is elevated in patients with angiosarcoma. Vaccination against TIE-2 + cells appears to reduce atheroma formation in experimental animals.
ANGPTL1, ANGPTL2, ANGPTL5, Angiopoietin 1, Angiopoietin 2, Angiopoietin 3, Angiopoietin 4, TIE1, TIE2.