1-Arachidoyl Lysophosphatidic Acid sodium
Referentie NB-64-44376-50mg
Formaat : 50mg
Merk : Neo Biotech
1-Arachidoyl Lysophosphatidic Acid sodium (Synonyms: LPA(20:0), 1-Eicosanoyl-Lysophosphatidic Acid, 1-Arachido...)
Catalog No. T83879 Copy Product Info
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 µM, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 µM, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free environment. This compound has also been detected in human urine.
1-Arachidoyl Lysophosphatidic Acid sodium
Copy Product InfoSynonyms LPA(20:0), 1-Eicosanoyl-Lysophosphatidic Acid, 1-Arachidoyl LPA
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 µM, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 µM, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free environment. This compound has also been detected in human urine.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium mobilization in primary human lung fibroblasts at an EC50 value of 3.6 µM, given these cells inherently express LPA1 but lack expression of LPA2-LPA6 receptors. Additionally, at a concentration of 2.5 µM, 1-arachidoyl LPA binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free environment. This compound has also been detected in human urine. |
| Synonyms | LPA(20:0), 1-Eicosanoyl-Lysophosphatidic Acid, 1-Arachidoyl LPA |
| Molecular Weight | 488.57 |
| Formula | C23H46O7P.Na |
| Smiles | O=C(OC[C@@H](O)COP(O)([O-])=O)CCCCCCCCCCCCCCCCCCC.[Na+] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | Ethanol: Soluble Methanol: Soluble |