Ac-LEHD-AMC [292633-16-0]
Referentie T36342-5mg
Formaat : 5mg
Merk : TargetMol
Ac-LEHD-AMC
Copy Product InfoAc-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Cas No. 292633-16-0
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. |
| Molecular Weight | 711.729 |
| Formula | C33H41N7O11 |
| Cas No. | 292633-16-0 |
| Smiles | CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: 1 mg/mL (1.41 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||