Anti-GLUT1 antibody

Referentie NB-22-52919-1

Formaat : 1mL

Merk : Neo Biotech

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Telefoonnummer : +1 850 650 7790

  • Anti-GLUT1 antibody

General Info

Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GLUT1 is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Purification: Affinity purified
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at 2-8°C upon receipt.

Information

Gene Symbol: SLC2A1
Gene ID: 6513
Uniprot ID: GTR1_HUMAN

Description

Tissue Specificity Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Post Translational Modifications Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization.
Function Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1
Glucose Transporter Type 1 - Erythrocyte/Brain
Glut-1
Hepg2 Glucose Transporter
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-196836
Reactome: R-HSA-422356
Reactome: R-HSA-5619043
Reactome: R-HSA-5653890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Melanosome
Photoreceptor Inner Segment
Localizes Primarily At The Cell Surface
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibody
Anti-Glucose Transporter Type 1 - Erythrocyte/Brain antibody
Anti-Glut-1 antibody
Anti-Hepg2 Glucose Transporter antibody
Anti-SLC2A1 antibody
Anti-GLUT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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