Anti-HER2/ERBB2 Antibody (2P27)
Referentie NB-64-117152-100uL
Formaat : 100uL
Merk : Neo Biotech
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Anti-HER2/ERBB2 Antibody (2P27)
(Synonyms: TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340) Copy Product InfoSynonyms: TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340
Catalog No. TMAC-01803 Copy Product Info
Anti-HER2/ERBB2 Antibody (2P27) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (2P27) can be used in ELISA,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HER2/ERBB2 Antibody (2P27) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (2P27) can be used in ELISA,IHC,WB. |
| Synonyms | TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340 |
| Clone | 2P27 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis using Her2 mouse mAb against SKBR3 (1) and MCF-7 (2) cell lysate.  |
| Application | ELISA IHC WB |
| Recommended Dose | ELISA: 1:10000; WB: 1:500-2000; IHC: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human Her2 |
| Antigen Species | Human |
| Uniprot ID | P04626 |
| Molecular Weight | Actual: 180 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Keywords
TKR-1TKR 1MLN-19HER 2ERVWE-1ERVWE 1ERBB-2ERBB 2EGFR-2EGFR 2CD-340CD 340
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Related Tags: Anti-HER2/ERBB2 Antibody (2P27) molecular weight
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