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Anti-IL17F Polyclonal Antibody

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Referentie NB-64-157552-100uL

Formaat : 100uL

Merk : Neo Biotech


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Anti-IL17F Polyclonal Antibody

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Synonyms:

Catalog No. TMAB-07612 Copy Product Info
Anti-IL17F Polyclonal Antibody is a Rabbit antibody targeting IL17F. Anti-IL17F Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-IL17F Polyclonal Antibody is a Rabbit antibody targeting IL17F. Anti-IL17F Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
Sample:
RAW264.7 (Mouse) Cell Lysate at 30 μg
JurkaT (Human) Cell Lysate at 30 μg
HL-60 (Human) Cell Lysate at 30 μg
LOVo (Human) Cell Lysate at 30 μg
Primary: Anti-IL17F (TMAB-07612) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 22 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityExpressed in activated, but not resting, CD4+ T-cells and activated monocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundIL-17F is a member of IL-17 family of structurallyrelated cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F is a homodimer of two 133 amino acid chains that are secreted by activated CD4+ Tcells and activated monocytes. The biological activities mediated by IL-17F are similar to those of IL-17. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony stimulating factor. It can also regulate cartilage matrix turnover, stimulate PBMC and T cell proliferation, and inhibit angiogenesis. This recombinant human IL-17F is produced by human cells. Biological activity: The activity was measured by its ability to induce IL-6 expression in the NHDF adult fibroblasts. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IL-17F
Antigen Species
Human
Gene Name
IL17F
Gene ID
112744
Protein Name
Interleukin-17F
Uniprot ID
Q96PD4
Function
Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.
Chemical Properties
Molecular WeightTheoretical: 17 kDa. Actual: 22 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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