Anti-Septin 6 Antibody

Referentie MBS821924-0,03mL

Formaat : 0.03mL

Merk : MyBiosource


Septin 6 (SEP6) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821924

MBS821924 is an antibody targeting SEP6. Also known as Anti-Septin 6 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to Septin 6 More details

Product Overview

Online Datasheet in PDF
Product Name
Septin 6 (SEP6), Polyclonal Antibody
Full Product Name
Anti-Septin 6 Antibody
Product Gene Name
anti-SEP6 antibody
Product Synonym Names
KIAA0128; SEP2; Septin-6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Septin 6 protein.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Septin 6 peptide (MBS822628) is used for blocking the activity of Septin 6 antibody (MBS821924)
OMIM
300683
3D Structure
ModBase 3D Structure for Q14141
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Septin 6. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SEP6 antibody
Western Blot (WB)
Application Notes for anti-SEP6 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-SEP6 antibody

Western blot analysis of Septin 6 expression in Jurkat (A), NIH3T3 (B), PC12 (C) whole cell lysates.
Rabbit Anti-SEP6 Polyclonal Antibody – Cat# MBS821924

Other Notes

Small volumes of anti-SEP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SEP6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
septin-6 isoform B
NCBI Official Synonym Full Names
septin 6
NCBI Official Symbol
SEPT6
NCBI Official Synonym Symbols
SEP2; SEPT2
UniProt Protein Name
Septin-6
Protein Family
Septin
UniProt Gene Name
SEPT6
UniProt Synonym Gene Names
KIAA0128; SEP2
UniProt Entry Name
SEPT6_HUMAN
NCBI Protein Information
septin-6; septin 2

NCBI Summary for SEP6

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for SEP6

SEPT6: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Belongs to the septin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: synaptic vesicle; spindle; nerve terminal; midbody; cleavage furrow

Molecular Function: protein binding; GTP binding

Biological Process: viral reproduction; cytokinesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SEP6 antibody

 Reference Product  PubMed Publications
 SEPT7 antibody  >24 publications with SEP6 and SEPT7
 SEPT2 antibody  >22 publications with SEP6 and SEPT2
 SEPT12 antibody  >3 publications with SEP6 and SEPT12
 SOCS7 antibody  >2 publications with SEP6 and SOCS7
 S100A4 antibody  >1 publications with SEP6 and S100A4
 hnRNP-A1 antibody  >1 publications with SEP6 and hnRNP-A1

Pathways associated with anti-SEP6 antibody

 Products by Pathway  Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram

Diseases associated with anti-SEP6 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with SEP6 and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with SEP6 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >2 publications with SEP6 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >2 publications with SEP6 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with SEP6 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with SEP6 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with SEP6 and Disease Models, Animal
 Atrophy Antibodies  >1 publications with SEP6 and Atrophy
 Neoplasms, Experimental Antibodies  >1 publications with SEP6 and Neoplasms, Experimental
 Liver Neoplasms, Experimental Antibodies  >1 publications with SEP6 and Liver Neoplasms, Experimental

Organs/Tissues associated with anti-SEP6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with SEP6 and Brain
 Blood Antibodies  >7 publications with SEP6 and Blood
 Liver Antibodies  >4 publications with SEP6 and Liver
 Nerve Antibodies  >3 publications with SEP6 and Nerve
 Bone Marrow Antibodies  >2 publications with SEP6 and Bone Marrow
 Embryonic Tissue Antibodies  >2 publications with SEP6 and Embryonic Tissue
 Bone Antibodies  >2 publications with SEP6 and Bone
 Heart Antibodies  >2 publications with SEP6 and Heart
 Eye Antibodies  >1 publications with SEP6 and Eye
 Muscle Antibodies  >1 publications with SEP6 and Muscle