Product Info Summary
| SKU: | A00379-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, ICC, WB |
Customers Who Bought This Also Bought
Cytoplasmic and Nuclear Protein Extraction Kit (AR0106)
Product info
Product Name
Anti-Survivin BIRC5 Antibody
SKU/Catalog Number
A00379-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Survivin BIRC5 Antibody (Catalog # A00379-1). Tested in ELISA, WB, ICC, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
Survivin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Survivin BIRC5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00379-1)
Host
Rabbit
Contents
Survivin Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Anti-Survivin antibody was raised against a peptide corresponding to 12 amino acids near the amino terminus of human Survivin. The immunogen is located within the first 50 amino acids of Survivin.
Reactive Species
A00379-1 is reactive to BIRC5 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
16.4 kDa
Background of BIRC5
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question