Anti-TIE1 Antibody (6A314)

Referentie NB-64-119384-50uL

Formaat : 50uL

Merk : Neo Biotech


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Anti-TIE1 Monoclonal Antibody (9H277)

(Synonyms: TIE, JTK14) Copy Product Info

Synonyms: TIE, JTK14

Catalog No. TMAC-04040 Copy Product Info
Anti-TIE1 Monoclonal Antibody (9H277) is a Mouse antibody targeting TIE1. Anti-TIE1 Monoclonal Antibody (9H277) can be used in WB,IHC.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-TIE1 Monoclonal Antibody (9H277) is a Mouse antibody targeting TIE1. Anti-TIE1 Monoclonal Antibody (9H277) can be used in WB,IHC.
SynonymsTIE, JTK14
Ig Type
IgG1
Clone
9H277
Reactivity
Human
Verified Activity
1. Western blot analysis of TIE1 on HepG2 cell lysate using anti-TIE1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CD68 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD68 antibody. Counter stained with hematoxylin.
Anti-TIE1 Monoclonal Antibody (9H277),Anti-TIE1 Monoclonal Antibody (9H277),Anti-TIE1 Monoclonal Antibody (9H277)
Application
WB
IHC
Recommended Dose
IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
Antigen Species
Human
Gene Name
TIE1
Gene ID
7075
Protein Name
Tyrosine-protein kinase receptor Tie-1
Uniprot ID
P35590
Chemical Properties
Molecular WeightTheoretical: 125 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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