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> Anti-Tryptophan Hydroxylase 1 Antibody (8M186)

Anti-Tryptophan Hydroxylase 1 Antibody (8M186)

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Referentie NB-64-123985-100uL

Formaat : 100uL

Merk : Neo Biotech


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Anti-Tryptophan Hydroxylase 1 Antibody (8M186)

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Catalog No. TMAY-02148 Copy Product Info
Anti-Tryptophan Hydroxylase 1 Antibody (8M186) is a Rabbit antibody targeting Tryptophan Hydroxylase 1. Anti-Tryptophan Hydroxylase 1 Antibody (8M186) can be used in ELISA.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-Tryptophan Hydroxylase 1 Antibody (8M186) is a Rabbit antibody targeting Tryptophan Hydroxylase 1. Anti-Tryptophan Hydroxylase 1 Antibody (8M186) can be used in ELISA.
Ig Type
Rabbit IgG
Clone
8M186
Reactivity
Human
Specificity
Human Tryptophan Hydroxylase 1/TPH1
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Tryptophan Hydroxylase 1 / TPH1 (rh Tryptophan Hydroxylase 1 / TPH1; TMPY-01959; P17752-1; Ile2-Ile444).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains one ACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. TPH1 expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells. The tryptophan hydroxylase 1 (TPH1) gene is also reported to be associated with suicidal behavior. Polymorphisms of TPH1 may assist in identifying a subgroup of mood disorder patients that is at higher risk for suicidal behavior.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Tryptophan Hydroxylase 1 / TPH1 protein (TMPY-01959)
Antigen Species
Human
Biology Area
Neurotransmitter Associated Enzymes
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Keywords

Tryptophan 5-monooxygenase 1Tryptophan 5-hydroxylase 1Tph1Tph 1Tph
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