Biotin-Linked Monoclonal Antibody to Interleukin 8 (IL8)
Referentie MBS2037231-0,2mL
Formaat : 0.2mL
Merk : MyBiosource
Interleukin 8 (IL8) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2037231SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2037231 is an antibody targeting IL8. Also known as Biotin-Linked Monoclonal Antibody to Interleukin 8 (IL8). Reactive in Human, Pig. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
Interleukin 8 (IL8), Monoclonal Antibody
Full Product Name
Biotin-Linked Monoclonal Antibody to Interleukin 8 (IL8)
Product Gene Name
anti-IL8 antibody
Product Synonym Names
CXCL8; AMCF-I; GCP1; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP1; SCYB8; TSG1; B-ENAP; Neutrophil-Activating Protein 1; Granulocyte Chemotactic Protein 1
Clonality
Monoclonal
Isotype
IgG
Clone Number
1-2#
Host
Mouse
Species Reactivity
Human, Pig
Form/Format
Liquid
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
500ug/ml (lot specific)
Specificity
The antibody is a mouse monoclonal antibody raised against IL8. It has been selected for its ability to recognize IL8 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Biotin Conjugated Antibody: IL8 Clone #1-2# (MBS2037231)
Immunogen: IL8 (MBS2011894)
Immunogen: IL8 (MBS2011894)
Matching Pairs
Unconjugated Antibody: IL8 Clone #1-2# (MBS2085814)
Biotin Conjugated Antibody: IL8 Clone #1-2# (MBS2037231)
Biotin Conjugated Antibody: IL8 Clone #1-2# (MBS2037231)
Molecular Weight
11,098 Da
OMIM
M17017 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Product Categories/Family for anti-IL8 antibody
Antibody labeling; Cytokine; Infection immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-IL8 antibody
Western Blot: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Other Notes
Small volumes of anti-IL8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IL8. It may not necessarily be applicable to this product.
NCBI Official Full Name
interleukin-8
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 8
NCBI Official Symbol
CXCL8
NCBI Official Synonym Symbols
IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
UniProt Protein Name
Interleukin-8
UniProt Synonym Protein Names
C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1
UniProt Gene Name
CXCL8
UniProt Synonym Gene Names
IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF
NCBI Protein Information
interleukin-8
NCBI Summary for IL8
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for IL8
IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular region
Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding
Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction
Show more Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular region
Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding
Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-IL8 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| ATF-2 Transcription Factor Network Pathway antibodies | ATF-2 Transcription Factor Network Pathway Diagram |
| Activation Of Genes By ATF4 Pathway antibodies | Activation Of Genes By ATF4 Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies | Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Chemokine Receptors Bind Chemokines Pathway antibodies | Chemokine Receptors Bind Chemokines Pathway Diagram |
Diseases associated with anti-IL8 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >675 publications with IL8 and Inflammation |
| Necrosis Antibodies | >395 publications with IL8 and Necrosis |
| Hypersensitivity Antibodies | >66 publications with IL8 and Hypersensitivity |
| Drug Toxicity Antibodies | >62 publications with IL8 and Drug Toxicity |
| Adenocarcinoma Antibodies | >49 publications with IL8 and Adenocarcinoma |
| Pulmonary Disease, Chronic Obstructive Antibodies | >48 publications with IL8 and Pulmonary Disease, Chronic Obstructive |
| Pneumonia Antibodies | >34 publications with IL8 and Pneumonia |
| Colorectal Neoplasms Antibodies | >30 publications with IL8 and Colorectal Neoplasms |
| Kidney Diseases Antibodies | >27 publications with IL8 and Kidney Diseases |
| Breast Neoplasms Antibodies | >26 publications with IL8 and Breast Neoplasms |
Organs/Tissues associated with anti-IL8 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >669 publications with IL8 and Blood |
| Lung Antibodies | >237 publications with IL8 and Lung |
| Vascular Antibodies | >201 publications with IL8 and Vascular |
| Intestine Antibodies | >90 publications with IL8 and Intestine |
| Skin Antibodies | >81 publications with IL8 and Skin |
| Liver Antibodies | >71 publications with IL8 and Liver |
| Heart Antibodies | >67 publications with IL8 and Heart |
| Bone Antibodies | >60 publications with IL8 and Bone |
| Muscle Antibodies | >59 publications with IL8 and Muscle |
| Brain Antibodies | >48 publications with IL8 and Brain |