Caspase 3 Colorimetric Cell-Based ELISA Kit
Referentie OKAG00580
Formaat : One96-WellPlate
Merk : Aviva Systems Biology
Caspase 3 Colorimetric Cell-Based ELISA Kit (OKAG00580)
| Datasheets/Manuals | Printable datasheet for Caspase 3 Colorimetric Cell-Based ELISA Kit (OKAG00580) |
|---|
| Predicted Species Reactivity | Homo sapiens|Human|Mouse|Rat |
|---|---|
| Product Format | 96-Well Microplate |
| Application | ELISA |
| ELISA Kit Detection Method | Colorimetric 450 nm |
| ELISA Kit Duration | 4.5 hours |
| ELISA Kit Range | At least 5000 cells/well |
| Additional Information | Dynamic Range: > 5000 Cells |
| :: | OMIM: 600636 UniGene: Hs.141125 |
| :: | Note: The product is for research use only, not for use in diagnostic or therapeutic procedures. |
| Reconstitution and Storage | 2°C to 8°C |
| Assay Info | Assay Type: Cell-Based Subtype: None Detection Method: Colorimetric 450 nm |
| Gene Symbol | CASP3 |
|---|---|
| Gene Full Name | caspase 3 |
| Alias Symbols | apopain, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, caspase-3, CPP-32, CPP32, CPP32B, cysteine protease CPP32, PARP cleavage protease, procaspase3, protein Yama, SCA-1, SREBP cleavage activity 1. |
| NCBI Gene Id | 836 |
| Protein Name | Caspase-3 |
| Description of Target | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
| Uniprot ID | P42574 |