Western Blot (Transfected lysate)

Western Blot analysis of CDK6 expression in transfected 293T cell line (H00001021-T03) by CDK6 MaxPab polyclonal antibody.

Lane 1: CDK6 transfected lysate(35.86 KDa).
Lane 2: Non-transfected lysate.

Immunoprecipitation

Immunoprecipitation of CDK6 transfected lysate using anti-CDK6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CDK6 MaxPab mouse polyclonal antibody (B01) (H00001021-B01).

Entrez GeneID

1021

GeneBank Accession#

NM_001259.1

Protein Accession#

NP_001250.1

Gene Name

CDK6

Gene Alias

MGC59692, PLSTIRE, STQTL11

Gene Description

cyclin-dependent kinase 6

Omim ID

603368

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. [provided by RefSeq

Other Designations

cell division protein kinase 6