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Cholesteryl linoleate [604-33-1]

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Referentie NB-64-29642-1g

Formaat : 1g

Merk : Neo Biotech

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Cholesteryl linoleate (Synonyms: Linoleic Acid cholesteryl ester, Cholesterol Linoleate, CE(18:2(9Z,12Z)))

Catalog No. T5214 Copy Product Info

Purity: 99.61%

Cholesteryl linoleate is the major cholesteryl ester in LDL and atherosclerotic lesions. It is present in LDL as a cholesteryl ester that is oxidized to form cholesteryl linoleate hydroperoxides using LDL receptor-associated proteins that are transferred to the plasma membranes of macrophages and CHO cells expressing 15-lipoxygenase.

Cholesteryl linoleate

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Synonyms Linoleic Acid cholesteryl ester, Cholesterol Linoleate, CE(18:2(9Z,12Z))

Cas No. 604-33-1

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Batch Information

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Purity:99.61%

Appearance:Viscous

Color:White

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Cholesteryl linoleate is the major cholesteryl ester in LDL and atherosclerotic lesions. It is present in LDL as a cholesteryl ester that is oxidized to form cholesteryl linoleate hydroperoxides using LDL receptor-associated proteins that are transferred to the plasma membranes of macrophages and CHO cells expressing 15-lipoxygenase.
Synonyms	Linoleic Acid cholesteryl ester, Cholesterol Linoleate, CE(18:2(9Z,12Z))

Chemical Properties

Molecular Weight	649.08
Formula	C₄₅H₇₆O₂
Cas No.	604-33-1
Smiles	CCCCC\C=C/C\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCCC(C)C
Relative Density.	0.96 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (77.03 mM), Sonication is recommended.

Chloroform: 10 mg/mL (15.41 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (3.85 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Chloroform/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5406 mL	7.7032 mL	15.4064 mL	77.0321 mL
5 mM	0.3081 mL	1.5406 mL	3.0813 mL	15.4064 mL
10 mM	0.1541 mL	0.7703 mL	1.5406 mL	7.7032 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.0770 mL	0.3852 mL	0.7703 mL	3.8516 mL
50 mM	0.0308 mL	0.1541 mL	0.3081 mL	1.5406 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.