QC Test

  • Specification

    Product Description

    Human DBI partial ORF ( NP_065438, 1 a.a. - 104 a.a.) recombinant protein with GST-tag at N-terminal.




    Wheat Germ (in vitro)

    Theoretical MW (kDa)


    Preparation Method

    in vitro wheat germ expression system


    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.


    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — DBI

    Entrez GeneID


    GeneBank Accession#


    Protein Accession#


    Gene Name


    Gene Alias

    ACBD1, ACBP, CCK-RP, EP, MGC70414

    Gene Description

    diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)

    Omim ID


    Gene Ontology


    Gene Summary

    This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq

    Other Designations

    GABA receptor modulator|acyl coenzyme A binding protein|acyl-Coenzyme A binding domain containing 1|cholecystokinin-releasing peptide, trypsin-sensitive|diazepam binding inhibitor|diazepam binding inhibitor, splice form 1c|endozepine

  • Interactome
  • Pathway
  • Disease