EEA1 antibody - N-terminal region
Referentie ARP30074_P050
Formaat : 100ul
Merk : Aviva Systems Biology
EEA1 Antibody - N-terminal region (ARP30074_P050)
| Datasheets/Manuals | Printable datasheet for anti-EEA1 (ARP30074_P050) antibody |
|---|
| Publications | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 |
|---|---|
| Tested Species Reactivity | Human, Rat |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, IP, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human EEA1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 75%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: LTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-EEA1 (ARP30074_P050) antibody is Catalog # AAP30074 (Previous Catalog # AAPH00250) |
| Other Applications Image 1 Data | IP Suggested Anti-EEA1 antibody Titration: 2 ug/ml Positive Control: Rat brain homogenate |
| Reference | Fratti,R.A., et al., (2003) J. Biol. Chem. 278 (47), 46961-46967 |
|---|---|
| Gene Symbol | EEA1 |
| Gene Full Name | Early endosome antigen 1 |
| Alias Symbols | MST105, ZFYVE2, MSTP105 |
| NCBI Gene Id | 8411 |
| Protein Name | Early endosome antigen 1 |
| Description of Target | EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25. |
| Uniprot ID | Q15075 |
| Protein Accession # | NP_003557 |
| Nucleotide Accession # | NM_003566 |
| Protein Size (# AA) | 1411 |
| Molecular Weight | 162kDa |
| Protein Interactions | UBC; RNF2; BMI1; CFTR; ERBB2; VCP; EEA1; RAB5A; TNK2; RABEP1; RABGEF1; PDCD6IP; PXK; HDAC6; ZFYVE16; USO1; STX6; RAB22A; STX12; TOM1; RAB5C; MAPK14; RAB5B; IGF1R; NSF; |
