CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signaling of B- and T-cells. Given that the antigen is located in the membrane of all B-cells, with the exception of plasma cells and some mature T-cells, Anti-CD45R exhibits specific reactivity with most B-lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B-cell lymphomas from T-cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B-cell lymphomas.

• IHC536-CD45RA Datasheet-IVD

• MSDS

CLONE:
IHC536

ISOTYPE:
IgG1, kappa

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Lymph Node, Tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD