Geranyl acetate [105-87-3]
Referentie T5607-1ml
Formaat : 1mLx10mM(inDMSO)
Merk : TargetMol
Geranyl acetate
Geranyl acetate
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Cas No. 105-87-3
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.03%
Appearance:Liquid
Color:Transparent
COA LCMS HNMR
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities. |
| In vitro | Studies on the antifungal activity especially Microsporum gypsum, Trichophyton vercossum and Candida tropicalis showed that geranyl acetate, its epoxide and hydroperoxide derivatives have good antifungal action[1].Geranyl acetate exhibited significant anticancer activity against colo-205 cancer cell line with IC50 values of 30 μM . To find out the underlying mechanism, DAPI staining was carried out and it was observed that both the monoterpenes, geraniol and geranyl acetate, induced apoptosis in colo-205 cells. The apoptosis was also associated with upregulation of Bax and downregulation of Bcl-2 expressions, indicative of mitochondrial apoptosis. Moreover, this monoterpenes could trigger DNA damage and G2/M cell cycle arrest in colo-205 cells[1]. |
| Cell Research | The antiproliferative activity was determined by MTT assay. Apoptosis was assessed by DAPI staining and DNA damage was checked by comet assay. The cell cycle analysis was carried out by flow cytometry and protein expression was examined by western blotting.[1]. |
| Molecular Weight | 196.29 |
| Formula | C12H20O2 |
| Cas No. | 105-87-3 |
| Smiles | CC(C)=CCCC(C)=CCOC(C)=O |
| Relative Density. | 0.91 |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (1273.63 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.19 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||