Human Acyl coenzyme A Thioesterase 8 (ACOT8) activation kit by CRISPRa

CAT#: GA106774

ACOT8 CRISPRa kit - CRISPR gene activation of human acyl-CoA thioesterase 8



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ACOT8
Locus ID 10005
Kit Components

GA106774G1, Acyl coenzyme A Thioesterase 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106774G2, Acyl coenzyme A Thioesterase 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106774G3, Acyl coenzyme A Thioesterase 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_005469, NM_183385, NM_183386
UniProt ID O14734
Synonyms hACTE-III; HNAACTE; hTE; NAP1; PTE-1; PTE-2; PTE1; PTE2
Summary The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010]

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