Human IgG1 lambda1, Isotype Control

Human IgG1 lambda1, Isotype Control, a human-derived antibody, is an isotype control for human IgG1λ1 antibody. Human IgG1 lambda1, Isotype Control can be used in the research of diabetes and pancreatic cancer^[1][2].

Human IgG1 lambda1, Isotype Control (48 h before supernatant collection) can be used in macrophages as a control for the inhibitory effect of the human OLR1 blocking antibody Golocdacimab (HY-P99646) on OLR1^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Human IgG1 lambda1, Isotype Control (20 mg/kg, s.c., once weekly; two doses) can be used as a control for Bimagrumab (HY-P99355) in diabetic pancreatic cancer mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA, FACS, Functional assay

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

141.84 kDa

Liquid

Colorless to light yellow

[Human IgG1 lambda1, Isotype Control]

Shipping with dry ice.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Papachristoforou E, et al. A Human Single-cell Atlas Identifies OLR1+ Scar-associated Macrophages as a Therapeutic Target for Chronic Liver Disease. bioRxiv, 2025: 2025.08. 27.671899.

  [2]. Ling YW, et al. Diabetes reshapes pancreatic cancer-associated endothelial niche by accelerating senescence. Nat Commun. 2025 Sep 30;16(1):8654.  [Content Brief]