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Impurity B of Calcitriol [66791-71-7]

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Referentie NB-64-02951-50mg

Formaat : 50mg

Merk : Neo Biotech

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Impurity B of Calcitriol (Synonyms: 1β,25-Dihydroxyvitamin-D3, 1-Epicalcitriol)

Catalog No. T11643 Copy Product Info

Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

Impurity B of Calcitriol

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Synonyms 1β,25-Dihydroxyvitamin-D3, 1-Epicalcitriol

Cas No. 66791-71-7

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Product Introduction

Bioactivity

Description	Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
In vitro	Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol exhibits antitumor activity; Calcitriol inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin, and brain carcinomas and myeloid leukemia cells.
Synonyms	1β,25-Dihydroxyvitamin-D3, 1-Epicalcitriol

Chemical Properties

Molecular Weight	416.64
Formula	C₂₇H₄₄O₃
Cas No.	66791-71-7
Smiles	17[C@@]1(CC[C@@]2(17)\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@@H](O)C1=C)[C@H](C)CCCC(C)(C)O
Relative Density.	1.06 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (240.02 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.92 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4002 mL	12.0008 mL	24.0015 mL	120.0077 mL
5 mM	0.4800 mL	2.4002 mL	4.8003 mL	24.0015 mL
10 mM	0.2400 mL	1.2001 mL	2.4002 mL	12.0008 mL
20 mM	0.1200 mL	0.6000 mL	1.2001 mL	6.0004 mL
50 mM	0.0480 mL	0.2400 mL	0.4800 mL	2.4002 mL
100 mM	0.0240 mL	0.1200 mL	0.2400 mL	1.2001 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.