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Isolongifolene [1135-66-6]

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Referentie NB-64-02995-10mg

Formaat : 10mg

Merk : Neo Biotech

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Isolongifolene (Synonyms: (-)-Isolongifolene)

Catalog No. T11685 Copy Product Info

Purity: 99.46%

Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative stress, mitochondrial dysfunction, and apoptosis by modulating the PI3K/AKT/GSK-3β signaling pathways.

Isolongifolene

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Synonyms (-)-Isolongifolene

Cas No. 1135-66-6

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Batch Information

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Purity:99.46%

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Product Introduction

Bioactivity

Description	Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative stress, mitochondrial dysfunction, and apoptosis by modulating the PI3K/AKT/GSK-3β signaling pathways.
In vitro	isolongifolene (ILF), a tricyclic sesquiterpene of Murraya koenigii, against rotenone-induced mitochondrial dysfunction, oxidative stress and apoptosis in a cellular model.
Synonyms	(-)-Isolongifolene

Chemical Properties

Molecular Weight	204.35
Formula	C₁₅H₂₄
Cas No.	1135-66-6
Smiles	04[C@]12CC[C@]3(C1)C(=CCCC3(C)C)C2(C)C
Relative Density.	0.930 g/cm3 at 20℃ (lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (122.34 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 1 mg/mL (4.89 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8936 mL	24.4678 mL	48.9356 mL	244.6782 mL
5 mM	0.9787 mL	4.8936 mL	9.7871 mL	48.9356 mL
10 mM	0.4894 mL	2.4468 mL	4.8936 mL	24.4678 mL
20 mM	0.2447 mL	1.2234 mL	2.4468 mL	12.2339 mL
50 mM	0.0979 mL	0.4894 mL	0.9787 mL	4.8936 mL
100 mM	0.0489 mL	0.2447 mL	0.4894 mL	2.4468 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.