ketohexokinase (KHK) (NM_000221) Human Untagged Clone
CAT#: SC315989
KHK (untagged)-Human ketohexokinase (fructokinase) (KHK), transcript variant a
Product Images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | ketohexokinase |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | >OriGene sequence for NM_000221 edited TCGAGATCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCATCTGACAAG CGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGGCAACCTGCT ACGGGAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCCGCTCGGGTCTTCG GGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGCTGCAGGTGG CTCCCTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAGCGGGGACAC CATCCTCCTGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCGGGCAGGAAG CTCTGGGAGTAGCCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGA CGTCATCAGCCTGGTGGACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCA GAGATGGCAGCGCGGAGGCAACGCGTCCAACTCCTGCACCATTCTCTCCCTGCTCGGAGC CCCCTGTGCCTTCATGGGCTCAATGGCTCCTGGCCATGTTGCTGATTTTGTCCTGGATGA CCTCCGCCGTTATTCTGTGGACCTACGCTACACAGTCTTTCAGACCACAGGCTCCGTCCC CATCGCCACGGTCATCATCAACGAGGCCAGTGGTAGCCGCACCATCCTATACTATGACAG GAGCCTGCCAGATGTGTCTGCTACAGACTTTGAGAAGGTTGATCTGACCCAGTTCAAGTG GATCCACATTGAGGGCCGGAACGCATCGGAGCAGGTGAAGATGCTGCAGCGGATAGACGC ACACAACACCAGGCAGCCTCCAGAGCAGAAGATCCGGGTGTCCGTGGAGGTGGAGAAGCC ACGAGAGGAGCTCTTCCAGCTGTTTGGCTACGGAGACGTGGTGTTTGTCAGCAAAGATGT GGCCAAGCACTTGGGGTTCCAGTCAGCAGAGGAAGCCTTGAGGGGCTTGTATGGTCGTGT GAGGAAAGGGGCTGTGCTTGTCTGTGCCTGGGCTGAGGAGGGCGCCGACGCCCTGGGCCC TGATGGCAAATTGCTCCACTCGGATGCTTTCCCGCCACCCCGCGTGGTGGATACACTGGG AGCTGGAGACACCTTCAATGCCTCCGTCATCTTCAGCCTCTCCCAGGGGAGGAGCGTGCA GGAAGCACTGAGATTCGGGTGCCAGGTGGCCGGCAAGAAGTGTGGCCTGCAGGGCTTTGA TGGCATCGTGTGAGAGCAGGTGCCGGCTCCTCACACACCATGGAGACTACCATTGCGGCT GCATCGCCTTCTCCCCTCCATCCAGCCTGGCGTCCAGGTTGCCCTGTTCAGGGGACAGAT GCAAGCTGTGGGGAGGACTCTGCCTGTGTCCTGTGTTCCCCACAGGGAGAGGCTCTGGGG GGATGGCTGGGGGATGCAGAGCCTCAGAGCAAATAAATCTTCCTCAGAGCCAAAAAAAAA AAAAAAAAAA >OriGene 5' read for NM_000221 unedited GAGACAGATGTATACGACTCCTATAGGGCGGCCGCGAACTCTCAGATCTGGTACCGATAT CAAGCTTGTCGAGATTCGCTTAGCCGCGCTTTAAAAAGGTTTGCATCAGCTGTGAGTCCA TCTGACAAGCGAGGAAACTAAGGCTGAGAAGTGGGAGGCGTTGCCATCTGCAGGCCCAGG CAACCTGCTACGGGAAGACCGGGGACCAAGACCTCTGGGTTGGCTTTCCTAGACCCGCTC GGGTCTTCGGGTGTCGCGAGGAAGGGCCCTGCTCCTTTCGTTCCCTGCACCCCTGGCCGC TGCAGGTGGCTCCCTGGAGGAGGAGCTCCCACGCGGAGGAGGAGCCAGGGCAGCTGGGAG CGGGGACACCATCCTCCTGGATAAGAGGCAGAGGCCGGGAGGAACCCCGTCAGCCGGGCG GGCAGGAAGCTCTGGGAGTAGCCTCATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGT GGTGCTGGACGTCATCAGCCTGGTGGACAAGTACCCTAAGGAGGACTCGGAGATAAGGTG TTTGTCCCAGAGATGGCAGCGCGGAGGCAACGCGTCCAACTCCTGCACCATTCTCTCCCT GCTCGGAGCCCCCTGTGCCTTCATGGGCTCAATGGCTCCTGGCCATGTTGCTGATTTTGT CCTGGATGACCTCCGCCGTTATTCTGTGGACCTACGCTACACAGTCTTTCAGACCACAGG CTCCGTCCCCATCGCCACGGTCATCATCAACGAGGCCAGTGGTAGCCGCACCATCCTATA CTATGACAGGAGCCTGCCAGATGTGTCTGCTACAGACTTTGAGATGTTGATCTGACCCAG TTCAAGTGGATCCACATTGAGGGCCGGACGCATCGGAGCAGTGAAGATGCTGCAGCGATA GACGCACACACACCAGCAGCCTCCAGAGCAGAGATCCGGTGTCCGTGGGAGGTGGAGAAG CCACGGAGAGGAGCTCTTTCAG |
| Restriction Sites | Please inquire |
| ACCN | NM_000221 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a good match to NM_000221.2 except for one SNP. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000221.1, NP_000212.1 |
| RefSeq Size | 1899 bp |
| RefSeq ORF | 897 bp |
| Locus ID | 3795 |
| UniProt ID | P50053 |
| Cytogenetics | 2p23.3 |
| Domains | pfkB |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism, Metabolic pathways |
| Gene Summary | This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant utilizes the alternate exon 3a and encodes isoform a, which exhibits lower enzymatic activity than isoform b. |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| RC202424 | KHK (Myc-DDK-tagged)-Human ketohexokinase (fructokinase) (KHK), transcript variant a | 300,00 EUR | |
| RC202424L3 | Lenti ORF clone of Human ketohexokinase (fructokinase) (KHK), transcript variant a, Myc-DDK-tagged | 600,00 EUR | |
| RC202424L4 | Lenti ORF clone of Human ketohexokinase (fructokinase) (KHK), transcript variant a, mGFP tagged | 600,00 EUR | |
| RG202424 | KHK (tGFP-tagged) - Human ketohexokinase (fructokinase) (KHK), transcript variant a | 500,00 EUR |