Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.

L-Ornithine [70-26-8]

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Referentie T0737-200mg

Formaat : 200mg

Merk : TargetMol

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L-Ornithine

(Synonyms: (S)-2,5-Diaminopentanoic acid) Copy Product Info

L-Ornithine ((S)-2, 5-diaminopentanoic acid) is a non-protein amino acid. L-Ornithine is mainly used in the urea cycle to remove excess nitrogen from the body. L-Ornithine is renoprotective. L-Ornithine has antifatigue effects.

Cas No. 70-26-8

For research use only—not for human use. No sales to individuals. Use as intended only.

Batch Information

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Purity:99.91%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Information

Bioactivity

Description	L-Ornithine ((S)-2, 5-diaminopentanoic acid) is a non-protein amino acid. L-Ornithine is mainly used in the urea cycle to remove excess nitrogen from the body. L-Ornithine is renoprotective. L-Ornithine has antifatigue effects.
Targets & IC50	Arginase (bovine):1.02 mM (Ki)
In vitro	METHODS: HK-2 cells were treated with L-Ornithine (100, 300 μM) for 24 hours, and ROS levels were measured using fluorescence microscopy. RESULTS: Ornithine protected HK-2 cells from ROS production. [1]
In vivo	METHODS: To investigate the effect of L-Ornithine on peripheral clock gene expression, mice were orally treated with L-Ornithine (1000 mg/kg) for 3 days. RESULTS: The phase of PER2 gene expression in liver, submandibular gland and kidney was significantly advanced in L-Ornithine treated mice. [2] METHODS: To investigate the effect of L-Ornithine on sleep behavior, L-Ornithine was added to the diet of maternal mice, and its effect on the sleep behavior of offspring mice was observed. RESULTS: L-Ornithine supplementation increased sleep-like behavior in mice. [3] METHODS: To study the effect of L-Ornithine on acute necrotizing pancreatitis, rats were intraperitoneally injected with L-Ornithine (3 g/kg). RESULTS: Severe acute necrotizing pancreatitis was induced by L-Ornithine in rats. [4]
Synonyms	(S)-2,5-Diaminopentanoic acid

Chemical Properties

Molecular Weight	132.16
Formula	C₅H₁₂N₂O₂
Cas No.	70-26-8
Smiles	NCCC[C@H](N)C(O)=O
Relative Density.	1.165 g/cm3

Storage & Solubility Information

Storage

Store under nitrogen,Keep away from direct sunlight,Keep away from moisture, Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: Insoluble

H2O: 50 mg/mL (378.33 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	7.5666 mL	37.8329 mL	75.6659 mL	378.3293 mL
5 mM	1.5133 mL	7.5666 mL	15.1332 mL	75.6659 mL
10 mM	0.7567 mL	3.7833 mL	7.5666 mL	37.8329 mL
20 mM	0.3783 mL	1.8916 mL	3.7833 mL	18.9165 mL
50 mM	0.1513 mL	0.7567 mL	1.5133 mL	7.5666 mL
100 mM	0.0757 mL	0.3783 mL	0.7567 mL	3.7833 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Product Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ornithine decarboxylase antizyme 1Ornithine carbamoyltransferaseOrnithine aminotransferaseL-OrnithineLOrnithineL OrnithineInhibitorinhibitEndogenousMetaboliteEndogenous MetaboliteArginase-2Arginase-1AminoAcidsandDerivativesAmino Acids and Derivatives2,5-Diaminopentanoic acid