L-SelenoMethionine [3211-76-5]

Referentie orb1689898-50mg

Formaat : 50mg

Merk : Biorbyt


L-SelenoMethionine

SKU: orb1689898

Description

L-SelenoMethionine

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3211-76-5
MW196.11
Purity98.55% (May vary between batches)
FormulaC5H11NO2Se
SMILES[C@@H](C(O)=O)(CC[Se]C)N
TargetAmino Acids and Derivatives|||Apoptosis|||Endogenous Metabolite
SolubilityDMSO:< 1 mg/mL (insoluble or slightly soluble);H2O:27.5 mg/mL (140.23 mM)

Bioactivity

In Vitro
At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells . c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

peroxidase, selenium, inhibit, L-(+)-Selenomethionine, L SelenoMethionine, L-SelenoMethionine, LSelenoMethionine, Inhibitor, Endogenous Metabolite, EndogenousMetabolite, glutathione, dietary, chemopreventive, cancer, Amino Acids and Derivatives, AminoAcidsandDerivatives, Apoptosis
  • Methylseleno carboxyethylglutamine HCl [orb2664838]

    100.00% (May vary between batches)

    347.65

    C9H17ClN2O5Se

    25 mg, 10 mg, 100 mg, 50 mg, 5 mg, 1 mg
  • L-Selenomethionine [orb1221017]

    >98% (HPLC)

    3211-76-5

    196.1

    C5H11NO2Se

    200 mg, 1 g, 500 mg, 100 mg, 50 mg

Key Properties

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Protocol Information