Lanolin [8006-54-0]

Biological Activity

Lanolin is a complex waxy substance composed of varying quantities of long-chain waxy esters and lanolin alcohols, acids and polycarbons, used as adjuvant. Lanolin has been used as a constituent of VALAP (Vaseline, lanolin, paraffin) to stabilize glass slides during worm-immobilization method. 

Soluble in ether, petroleum ether, chloroform and petroleum benzene. Insoluble in water.

Product Citations

• 

  Vopr Virusol. 2011 Apr ;56(2):41-6.

  Evaluation of the efficiency and reactogenicity of emulsion-based adjuvant systems in the manufacture of polyclonal enteroviral diagnostic sera
  Lanolin purchased from AbMole

Protocol (for reference only)

Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time

Animal Experiment
Animal models
Formulation
Dosages
Administration

Chemical Information

CAS Number	8006-54-0
Solubility (25°C)	Soluble in ether Soluble in petroleum ether Soluble in chloroform Soluble in petroleum benzene
Storage	2-8°C, dry, sealed, protect from light

References

[1] J Freund, et al. Science. IMMUNIZATION AGAINST MALARIA: VACCINATION OF DUCKS WITH KILLED PARASITES INCORPORATED WITH ADJUVANTS

[2] C C OPRESCU. Stud Cercet Inframicrobiol. Allergic sensitization of guinea pigs to Escherichia coli in presence of chloroform-soluble lipids of Mycobacterium tuberculosis and of certain adjuvants (lanolin and paraffin oil)

[3] P C Klykken, et al. Curr Top Microbiol Immunol. The adjuvancy of silicones: dependency on compartmentalization