Latrophilin 1 antibody
Referentie GTX87108-100ug
Formaat : 100ug
Merk : Genetex
Host | Rabbit |
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Clonality | Polyclonal |
Isotype | IgG |
Application | ICC/IF |
Reactivity | Human |
Package | 100 μg |
View product citations for antibody GTX87108 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
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ICC/IF | 1:100~1:500 |
Not tested in other applications.
Calculated MW
163 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Latrophilin 1 (561-610).
Purification
Purified by antigen-affinity chromatography
From serum
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
ADGRL1 , CIRL1 , CL1 , LEC2 , LPHN1 , adhesion G proteincoupled receptor L1 , Latrophilin-1 , adhesion G protein-coupled receptor L1
Cellular Localization
Cell membrane,Cell projection,Axon,Cell projection,Growth cone,Cell junction,Synapse,Cell junction,Synapse,Presynaptic cell membrane,Cell junction,Synapse,Synaptosome
Background
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
Database
DATA IMAGES
GTX87108 ICC/IF ImageICC/IF analysis of LOVO cells using GTX87108 Latrophilin 1 antibody. The picture on the right is blocked with the synthesized peptide. |
REVIEW
SDS | |
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PBS.pdf | |
Glycerol.pdf | |
Sodium Azide.pdf |