Formaat : 25mg
| Size : | Quantity | ||
|---|---|---|---|
| 25 mg | $80.00 | ||
| 100 mg | $240.00 |
Leupeptin hemisulfate (103476-89-7) is a reversible inhibitor of trypsin-like proteases and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B, H and L.1-3 Blocks various apoptotic pathways in T cells.4 Commonly used in cell lysis buffers to protect proteins from degradation. Typical working concentration is 1µM (0.5 µg/ml).
References/Citations:
1) Aoyagi et al. (1969), Leupeptins, new protease inhibitors from Actinomycetes; J. Antibiot., 22 283
2) Barrett et al. (1981), Cathepsin B, Cathepsin H and Cathepsin L; Methods Enzymol., Pt C, 80 535
3) Knight et al. (1980), Human cathepsin B. Application of the substrate N-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide to a study of the inhibition by leupeptin; Biochem. J., 189 447
4) Sarin et al. (1995), A protease-dependent TCR-induced death pathway in mature lymphocytes; J. Immunol., 154 5806
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Leupeptin hemisulfate (103476-89-7) is a reversible inhibitor of trypsin-like proteases and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B, H and L.1-3 Blocks various apoptotic pathways in T cells.4 Commonly used in cell lysis buffers to protect proteins from degradation. Typical working concentration is 1µM (0.5 µg/ml).
References/Citations:
1) Aoyagi et al. (1969), Leupeptins, new protease inhibitors from Actinomycetes; J. Antibiot., 22 283
2) Barrett et al. (1981), Cathepsin B, Cathepsin H and Cathepsin L; Methods Enzymol., Pt C, 80 535
3) Knight et al. (1980), Human cathepsin B. Application of the substrate N-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide to a study of the inhibition by leupeptin; Biochem. J., 189 447
4) Sarin et al. (1995), A protease-dependent TCR-induced death pathway in mature lymphocytes; J. Immunol., 154 5806
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