Linalyl acetate-d6

Linalyl acetate-d₆ is deuterated labeled Linalyl acetate (HY-N6948). Linalyl acetate is the principal components of many plant essential oils. Linalyl acetate exhibits anti-anxiety, anti-inflammatory, anti-diabetic, anti-stress, and cardiovascular-regulatory effects. Linalyl acetate is orally active^[1][2][3][4].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. A.T. Peana, et al. Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils,Phytomedicine. 2002 Dec;9(8):721-6.  [Content Brief]

  [3]. Rani M, et al. Evaluation of antianxiety activity of Linalyl acetate in Swiss albino Mice[J]. Ann Romanian Soc Cell Biol, 2022, 26(1): 3470-3482.

  [4]. Kim JR, et al., Cardiovascular effects of linalyl acetate in acute nicotine exposure. Environ Health Prev Med. 2017 Apr 24;22(1):42.  [Content Brief]

  [5]. Seo E, et al., Linalyl acetate as a potential preventive agent against muscle wasting in rheumatoid arthritis rats chronically exposed to nicotine. J Pharmacol Sci. 2021 Sep;147(1):27-32.  [Content Brief]