Lutein [127-40-2]
Referentie T3S1858-50mg
Formaat : 50mg
Merk : TargetMol
Lutein
(Synonyms: Xantofyl, Xanthophyll, Vegetable Lutein) Copy Product Info
1. Lutein (Xantofyl) has antitumour action. 2. Lutein has antimutagenic action. 3. Lutein has a wide range of antimicrobial action. 4. Lutein is potentially useful for treating macular degeneration.
Cas No. 127-40-2
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.01%
Appearance:Solid
Color:Orange
COA LCMS HNMR
Product Introduction
Lutein AI Summary
Lutein exhibits a range of notable bioactivities and chemical properties. It is particularly bioactive as an inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1), with a potency of 26608.6 nM in cells in the absence of CPT, and shows gametocytocidal activity with a potency of 25118.9 nM. The compound demonstrates significant antioxidant activity, inhibiting antimycin-induced mitochondrial ROS production by 89.7% at 10 µM in mouse 661W cells. Additionally, Lutein possesses antiviral activity, inhibiting SARS-CoV-2 induced cytotoxicity in Caco-2 cells at 10 µM with an inhibition rate of 17.37%, as well as in VERO-6 cells, though with a slightly lower inhibition rate of -0.03%. It also inhibits the SARS-CoV-2 3CL-Pro protease by 8.322% at a concentration of 20 µM. Chemically, Lutein has a log POW value of 3.89, indicating its lipophilicity and higher affinity for lipid-based substances. The compound's stability and ratios can vary significantly depending on food sources and preparation methods, with the highest ratios found in raw blackberries and raw paprika. Lastly, Lutein shows mild inhibitory activity in enzymatic assays of human HDAC6..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 1. Lutein (Xantofyl) has antitumour action. 2. Lutein has antimutagenic action. 3. Lutein has a wide range of antimicrobial action. 4. Lutein is potentially useful for treating macular degeneration. |
| Synonyms | Xantofyl, Xanthophyll, Vegetable Lutein |
| Molecular Weight | 568.87 |
| Formula | C40H56O2 |
| Cas No. | 127-40-2 |
| Smiles | C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)C[C@H](O)CC1C)\C)\C)/C)/C)\[C@@H]2C(C)(C)C[C@@H](O)C=C2C |
| Relative Density. | 0.9944 g/cm3 (Estimated) |
| Storage | Keep away from direct sunlight,Store at low temperature,Keep away from moisture Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 10.5 mg/mL (18.46 mM), Sonication is recommended.  H2O: Insoluble Ethanol: 10 mg/mL (17.58 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
Ethanol/DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||