Monkey Insulin, INS ELISA Kit

Referentie MBS701773-5x96

Formaat : 5x96-Strip-Wells

Merk : MyBiosource


Insulin, INS (INS) ELISA Kit for Monkey

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS701773

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for INS has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP)… More details

Product Overview

Online Datasheet in PDF
Product Name
Insulin, INS, ELISA Kit
Full Product Name
Monkey Insulin, INS ELISA Kit
Product Gene Name
INS elisa kit
Product Synonym Names
Monkey Insulin; INS ELISA Kit; Monkey Insulin; INS
Species Reactivity
Monkey
Assay Type
Quantitative Sandwich
Samples
Serum, plasma
Detection Range
10 uIU/ml-160 uIU/ml
Sensitivity
< 2 uIU/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of monkey INS. No significant cross-reactivity or interference between monkey INS and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
21,537 Da
OMIM
613370
3D Structure
ModBase 3D Structure for P01308
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of INS elisa kit

Monkey INS ELISA Kit – Cat# MBS701773

Other Notes

Small volumes of INS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INS purchase

MBS701773 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin, INS, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing INS. The ELISA analytical biochemical technique of the MBS701773 kit is based on INS antibody-INS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect INS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, INS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for INS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
insulin
NCBI Official Synonym Full Names
insulin
NCBI Official Symbol
INS
NCBI Official Synonym Symbols
ILPR; IRDN; IDDM1; IDDM2; MODY10
UniProt Protein Name
Insulin
Protein Family
Insulin
UniProt Gene Name
INS
UniProt Entry Name
INS_HUMAN
NCBI Protein Information
insulin; proinsulin; preproinsulin; insulin-dependent diabetes mellitus 2

NCBI Summary for INS

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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UniProt Comments for INS

Function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with INS elisa kit

 Reference Product  PubMed Publications
 IRS1 elisa kit  >35 publications with INS and IRS1
 FOXO1 elisa kit  >31 publications with INS and FOXO1
 INSR elisa kit  >27 publications with INS and INSR
 IRS2 elisa kit  >26 publications with INS and IRS2
 AKT1 elisa kit  >18 publications with INS and AKT1
 GRB2 elisa kit  >11 publications with INS and GRB2
 IDE elisa kit  >7 publications with INS and IDE
 IGFBP1 elisa kit  >5 publications with INS and IGFBP1
 AKT2 elisa kit  >3 publications with INS and AKT2
 PTPN1 elisa kit  >3 publications with INS and PTPN1

Pathways associated with INS elisa kit

 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram

Diseases associated with INS elisa kit

 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >1080 publications with INS and Metabolic Diseases
 Diabetes Mellitus Antibodies  >894 publications with INS and Diabetes Mellitus
 Insulin Resistance Antibodies  >326 publications with INS and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >307 publications with INS and Diabetes Mellitus, Type 2
 Obesity Antibodies  >241 publications with INS and Obesity
 Hyperglycemia Antibodies  >219 publications with INS and Hyperglycemia
 Hyperinsulinism Antibodies  >213 publications with INS and Hyperinsulinism
 Hypertension Antibodies  >129 publications with INS and Hypertension
 Polycystic Ovary Syndrome Antibodies  >59 publications with INS and Polycystic Ovary Syndrome
 Fatty Liver Antibodies  >48 publications with INS and Fatty Liver

Organs/Tissues associated with INS elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1326 publications with INS and Blood
 Pancreas Antibodies  >1266 publications with INS and Pancreas
 Brain Antibodies  >639 publications with INS and Brain
 Muscle Antibodies  >509 publications with INS and Muscle
 Liver Antibodies  >346 publications with INS and Liver
 Heart Antibodies  >263 publications with INS and Heart
 Vascular Antibodies  >242 publications with INS and Vascular
 Kidney Antibodies  >224 publications with INS and Kidney
 Nerve Antibodies  >219 publications with INS and Nerve
 Bone Antibodies  >140 publications with INS and Bone

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