Mouse Prostaglandin E2 (PGE2) ELISA Kit
Referentie MBS266212-96
Formaat : 96-Strip-Wells
Merk : MyBiosource
Prostaglandin E2 (PGE2) ELISA Kit for Mouse
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS266212Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Mouse PGE2 monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and… More details
Product Overview
Product Name
Prostaglandin E2 (PGE2), ELISA Kit
Full Product Name
Mouse Prostaglandin E2 (PGE2) ELISA Kit
Product Gene Name
PGE2 elisa kit
Species Reactivity
Mouse
Assay Type
Sandwich
Detection Range
500 pg/mL-7.8 pg/mL
Sensitivity
Up to 1 pg/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Inter-assay Precision
<= 12%
Intra-assay Precision
<= 8%
Molecular Weight
53,119 Da
OMIM
601586
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of PGE2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PGE2 purchase
MBS266212 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostaglandin E2 (PGE2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PGE2. The ELISA analytical biochemical technique of the MBS266212 kit is based on PGE2 antibody-PGE2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PGE2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PGE2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for PGE2. It may not necessarily be applicable to this product.
NCBI Official Full Name
prostaglandin E2 receptor EP4 subtype
NCBI Official Synonym Full Names
prostaglandin E receptor 4 (subtype EP4)
NCBI Official Symbol
PTGER4
NCBI Official Synonym Symbols
EP4; EP4R
UniProt Protein Name
Prostaglandin E2 receptor EP4 subtype
UniProt Synonym Protein Names
Prostanoid EP4 receptor
UniProt Gene Name
PTGER4
UniProt Synonym Gene Names
PTGER2; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype
UniProt Entry Name
PE2R4_HUMAN
NCBI Protein Information
prostaglandin E2 receptor EP4 subtype; prostanoid EP4 receptor; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype
NCBI Summary for PGE2
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for PGE2
PTGER4: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5p13.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: protein binding; prostaglandin E receptor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; T-helper cell differentiation; response to mechanical stimulus; regulation of stress fiber formation; negative regulation of inflammatory response; negative regulation of cytokine secretion; JNK cascade; response to lipopolysaccharide; immune response; negative regulation of integrin activation; regulation of ossification; positive regulation of inflammatory response; positive regulation of cytokine secretion
Show more Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5p13.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: protein binding; prostaglandin E receptor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; T-helper cell differentiation; response to mechanical stimulus; regulation of stress fiber formation; negative regulation of inflammatory response; negative regulation of cytokine secretion; JNK cascade; response to lipopolysaccharide; immune response; negative regulation of integrin activation; regulation of ossification; positive regulation of inflammatory response; positive regulation of cytokine secretion
Research Articles on PGE2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with PGE2 elisa kit
| Reference Product | PubMed Publications |
|---|---|
| PTGER2 elisa kit | >206 publications with PGE2 and PTGER2 |
| PTGS2 elisa kit | >146 publications with PGE2 and PTGS2 |
| PTH elisa kit | >7 publications with PGE2 and PTH |
| GNAS elisa kit | >2 publications with PGE2 and GNAS |
| POMC elisa kit | >1 publications with PGE2 and POMC |
Pathways associated with PGE2 elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| Eicosanoid Ligand-binding Receptors Pathway antibodies | Eicosanoid Ligand-binding Receptors Pathway Diagram |
| G Alpha (s) Signalling Events Pathway antibodies | G Alpha (s) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| GPCRs, Class A Rhodopsin-like Pathway antibodies | GPCRs, Class A Rhodopsin-like Pathway Diagram |
| Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies | Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram |
| Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies | Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram |
| Neuroactive Ligand-receptor Interaction Pathway antibodies | Neuroactive Ligand-receptor Interaction Pathway Diagram |
| Neuroactive Ligand-receptor Interaction Pathway antibodies | Neuroactive Ligand-receptor Interaction Pathway Diagram |
Diseases associated with PGE2 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >83 publications with PGE2 and Inflammation |
| Disease Models, Animal Antibodies | >59 publications with PGE2 and Disease Models, Animal |
| Necrosis Antibodies | >48 publications with PGE2 and Necrosis |
| Cardiovascular Diseases Antibodies | >40 publications with PGE2 and Cardiovascular Diseases |
| Carcinoma Antibodies | >33 publications with PGE2 and Carcinoma |
| Nervous System Diseases Antibodies | >31 publications with PGE2 and Nervous System Diseases |
| Heart Diseases Antibodies | >15 publications with PGE2 and Heart Diseases |
| Kidney Diseases Antibodies | >14 publications with PGE2 and Kidney Diseases |
| Breast Neoplasms Antibodies | >14 publications with PGE2 and Breast Neoplasms |
| Neoplasms, Experimental Antibodies | >14 publications with PGE2 and Neoplasms, Experimental |
Organs/Tissues associated with PGE2 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >125 publications with PGE2 and Blood |
| Vascular Antibodies | >62 publications with PGE2 and Vascular |
| Kidney Antibodies | >41 publications with PGE2 and Kidney |
| Brain Antibodies | >40 publications with PGE2 and Brain |
| Intestine Antibodies | >29 publications with PGE2 and Intestine |
| Lung Antibodies | >29 publications with PGE2 and Lung |
| Eye Antibodies | >22 publications with PGE2 and Eye |
| Connective Tissue Antibodies | >19 publications with PGE2 and Connective Tissue |
| Liver Antibodies | >19 publications with PGE2 and Liver |
| Skin Antibodies | >16 publications with PGE2 and Skin |
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