Mre11 antibody [12D7]

Referentie GTX70212-100ul

Formaat : 100ul

Merk : GeneTex


Mre11 antibody [12D7]

Cat. No. GTX70212
1 194
Cat. No.  GTX70212
KO/KD Comparison Orthogonal Carrier-Free
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image
KO/KD

Non-transfected (–) and transfected (+) HeLa whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image
Comparison

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membranes were blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:1000 and competitor's antibody diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image
Comparison

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membranes were blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:1000 and competitor's antibody diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

Mre11 antibody [12D7] detects Mre11 protein at nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Mre11 stained by Mre11 antibody [12D7] (GTX70212) diluted at 1:200.
Blue: Hoechst 33342 staining.
Scale bar= 10 μm.

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:500. The HRP-conjugated anti-mouset IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Mre11 antibody [12D7] detects Mre11 protein by western blot analysis.
A. 30 μg 293T whole cell extract
B. 30 μg whole cell extract of human Mre11-transfected 293T cells
7.5% SDS-PAGE
Mre11 antibody [12D7] (GTX70212) dilution: 1:1000
The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image
Orthogonal

The data was published in the journal Viruses in 2015.PMID: 26057167

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image
Orthogonal

The data was published in the journal J Virol in 2017.PMID: 28855246

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image
Orthogonal

The data was published in the journal PLoS Pathog in 2010.PMID: 20949077

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Nucleic Acids Res in 2016. PMID: 26446986

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Nucleic Acids Res in 2016. PMID: 26446986

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal BMC Biol in 2015. PMID: 25857663

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Nat Commun in 2017.PMID: 29042561

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Open Biol in 2015.PMID: 25924630

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal PLoS One in 2015.PMID: 25826455

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal BMC Cancer in 2014.PMID: 24928521

Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Open Biol in 2015.PMID: 25924630

Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Nat Commun in 2017.PMID: 29042561

This Mre11 antibody [12D7] (GTX70212) is a mouse monoclonal antibody validated for detection of Mre11 by WB, ICC/IF, IP, ELISA, Functional Assay, and PLA. Reactive to human samples. This product is cited in 194 published studies. Knockout/knockdown validation supports antibody specificity.
Summary
MRE11 antibody recognizes MRE11 protein, an enzyme with a predicted molecular weight of ~81 kDa. MRE11 forms the core of the MRN (MRE11-RAD50-NBS1) complex, one of the first components of the DNA damage response (DDR) to DNA double-strand breaks where it recruits other signaling factors required for repair. MRE11 has both exonuclease and endonuclease activities, and is responsible for the DNA binding of the complex.
See all Mre11 products

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