PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody
Referentie MBS4516450-0,2mg
Formaat : 0.2mg
Merk : MyBiosource
PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody
CD47 Antibody – Mouse
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4516450MBS4516450 is an antibody targeting CD47. Also known as PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody. Reactive in Human, Mouse, Rat. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
CD47, Antibody
Full Product Name
PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody
Product Gene Name
anti-CD47 antibody
Product Synonym Names
Leukocyte surface antigen CD47, Cd47, Integrin-associated protein, IAP
Isotype
Rat IgG2a, kappa
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Concentration
0.2mg/mL (lot specific)
Preparation and Storage
Store at 2~8 degree C and protected from prolonged exposure to light. Do not freeze.
Applications Tested/Suitable for anti-CD47 antibody
Flow Cytometry (FC/FACS/FCM)
Other Notes
Small volumes of anti-CD47 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD47. It may not necessarily be applicable to this product.
NCBI Official Full Name
Leukocyte surface antigen CD47
NCBI Official Synonym Full Names
CD47 molecule
NCBI Official Symbol
CD47
NCBI Official Synonym Symbols
IAP; OA3; MER6
UniProt Protein Name
Leukocyte surface antigen CD47
UniProt Synonym Protein Names
Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD_antigen: CD47
Protein Family
Leukocyte surface antigen
UniProt Gene Name
CD47
UniProt Synonym Gene Names
MER6; IAP
UniProt Entry Name
CD47_HUMAN
NCBI Protein Information
leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen identified by monoclonal antibody 1D
NCBI Summary for CD47
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Show more UniProt Comments for CD47
CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3q13.1-q13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; positive regulation of T cell activation; opsonization; blood coagulation; cell adhesion; leukocyte migration; positive regulation of inflammatory response
Show more Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3q13.1-q13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; positive regulation of T cell activation; opsonization; blood coagulation; cell adhesion; leukocyte migration; positive regulation of inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CD47 antibody
| Reference Product | PubMed Publications |
|---|---|
| THBS1 antibody | >141 publications with CD47 and THBS1 |
| SIRPA antibody | >72 publications with CD47 and SIRPA |
| RHAG antibody | >22 publications with CD47 and RHAG |
| PTPN11 antibody | >7 publications with CD47 and PTPN11 |
| SIRPB1 antibody | >5 publications with CD47 and SIRPB1 |
| SIRPG antibody | >3 publications with CD47 and SIRPG |
| THBS2 antibody | >1 publications with CD47 and THBS2 |
| ITGB3 antibody | >1 publications with CD47 and ITGB3 |
| ITGAV antibody | >1 publications with CD47 and ITGAV |
Pathways associated with anti-CD47 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Cell Surface Interactions At The Vascular Wall Pathway antibodies | Cell Surface Interactions At The Vascular Wall Pathway Diagram |
| Cell-Cell Communication Pathway antibodies | Cell-Cell Communication Pathway Diagram |
| ECM-receptor Interaction Pathway antibodies | ECM-receptor Interaction Pathway Diagram |
| ECM-receptor Interaction Pathway antibodies | ECM-receptor Interaction Pathway Diagram |
| Extracellular Matrix Organization Pathway antibodies | Extracellular Matrix Organization Pathway Diagram |
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Integrin Cell Surface Interactions Pathway antibodies | Integrin Cell Surface Interactions Pathway Diagram |
| Integrins In Angiogenesis Pathway antibodies | Integrins In Angiogenesis Pathway Diagram |
| Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies | Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram |
| Spinal Cord Injury Pathway antibodies | Spinal Cord Injury Pathway Diagram |
Diseases associated with anti-CD47 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Immune System Diseases Antibodies | >84 publications with CD47 and Immune System Diseases |
| Inflammation Antibodies | >81 publications with CD47 and Inflammation |
| Disease Models, Animal Antibodies | >46 publications with CD47 and Disease Models, Animal |
| Anemia Antibodies | >43 publications with CD47 and Anemia |
| Necrosis Antibodies | >42 publications with CD47 and Necrosis |
| Nervous System Diseases Antibodies | >33 publications with CD47 and Nervous System Diseases |
| Brain Diseases Antibodies | >28 publications with CD47 and Brain Diseases |
| Neoplasms, Experimental Antibodies | >23 publications with CD47 and Neoplasms, Experimental |
| Respiratory Tract Diseases Antibodies | >14 publications with CD47 and Respiratory Tract Diseases |
| Breast Neoplasms Antibodies | >10 publications with CD47 and Breast Neoplasms |
Organs/Tissues associated with anti-CD47 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >434 publications with CD47 and Blood |
| Vascular Antibodies | >105 publications with CD47 and Vascular |
| Bone Antibodies | >75 publications with CD47 and Bone |
| Bone Marrow Antibodies | >62 publications with CD47 and Bone Marrow |
| Brain Antibodies | >57 publications with CD47 and Brain |
| Muscle Antibodies | >54 publications with CD47 and Muscle |
| Lung Antibodies | >28 publications with CD47 and Lung |
| Liver Antibodies | >28 publications with CD47 and Liver |
| Spleen Antibodies | >27 publications with CD47 and Spleen |
| Skin Antibodies | >26 publications with CD47 and Skin |