Prostaglandin F2α ethanolamide [353787-70-9]
Referentie A9077-10mg
Formaat : 10mg
Merk : APExBIO Technology
Prostaglandin F2α ethanolamide
Catalog No.
A9077
Prostaglandin F2α ethanolamide is an ethanolamide-class G protein-coupled receptor (GPCR). It also acts as a luteolytic hormone in sheep and may serve as a nociceptive mediator in the spinal cord.
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Prostaglandin F2α ethanolamide is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues.1 AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs.It has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.
| Storage | Store at -20°C |
| M.Wt | 397.56 |
| Cas No. | 353787-70-9 |
| Formula | C22H39NO5 |
| Synonyms | Prostamide F2α，PGF2α-EA |
| Solubility | Soluble in DMSO |
| Chemical Name | (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)-N-(2-hydroxyethyl)hept-5-enamide |
| Canonical SMILES | CCCCC[C@@H](/C=C/[C@H]([C@@H](C/C=C\CCCC(NCCO)=O)[C@H](C1)O)[C@@H]1O)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
- Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
