PTP epsilon (PTPRE) Mouse Monoclonal Antibody [Clone ID: OTI5F2]

CAT#: TA500994

Anti-PTPRE (PTP epsilon) mouse monoclonal antibody, clone OTI5F2 (formerly 5F2)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP


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Specifications

Product Data
Clone Name OTI5F2
Applications IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.58 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 80.6 kDa
Gene Name protein tyrosine phosphatase receptor type E
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported,one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Synonyms HPTPE; PTPE; R-PTP-EPSILON
Reference Data
Protein Families Druggable Genome, Phosphatase, Transmembrane

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