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> Quinacrine mustard (dihydrochloride) [4213-45-0]

Quinacrine mustard (dihydrochloride) [4213-45-0]

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Referentie HY-W127705-5mg

Formaat : 5mg

Merk : MedChemExpress


Description

Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes[1][2][3].

In Vitro

Quinacrine mustard dihydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes[1].
Quinacrine mustard dihydrochloride (28 μM) increases the number of mutants that appeared after an exposure of bacteria[2].
quinacrine mustard dihydrochloride (0.2 μM; 4h) induces cell cycle arrest at G2+M-phase in HL-60 cells[3].
Caffeine (5 mM) prevents the cytotoxic action of quinacrine mustard dihydrochloride (0.2 μM; 4h) in HL-60 cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Quinacrine mustard dihydrochloride Related Antibodies

Cell Cycle Analysis[3]

Cell Line: HL-60 cells
Concentration: 0.2 µM
Incubation Time: 4 h
Result: Induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50%.
Masse moléculaire

541.77

Formule

C23H30Cl5N3O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(CCCN(CCCl)CCCl)N=C1C2=C(C=C(C=C2)Cl)NC3=C1C=C(C=C3)OC.Cl.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité
In Vitro: 

H2O : 6.25 mg/mL (11.54 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8458 mL 9.2290 mL 18.4580 mL
5 mM 0.3692 mL 1.8458 mL 3.6916 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation
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