Recombinant human Insulin-like growth factor II protein
Referentie OPCA00748-20UG
Formaat : 20ug
Merk : Aviva Systems Biology
PP1446 Recombinant Protein (Human) (OPCA00748)
| Datasheets/Manuals | Printable datasheet for PP1446 Recombinant Protein (Human) (OPCA00748) |
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| Predicted Species Reactivity | Homo sapiens|Human |
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| Product Format | Liquid or Lyophilized powder |
| Additional Information | Tag information : GST tag |
| Reconstitution and Storage | -20°C or -80°C |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Peptide Sequence | ETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK |
| Protein Sequence | ETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK |
| Storage Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Source | E.coli |
| Protein Range | 30-180 aa |
| Tag | N-terminal GST-tagged |
| Reference | Insulin-like growth factor II precursor gene organization in relation to insulin gene family.Dull T.J., Gray A., Hayflick J.S., Ullrich A.Nature 310:777-781(1984) |
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| Gene Symbol | IGF2 |
| Gene Full Name | insulin like growth factor 2 |
| Alias Symbols | C11orf43, GRDF, IGF-II, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor type 2, PP9974, preptin, Somatomedin-A, SRS3, T3M-11-derived growth factor. |
| NCBI Gene Id | 3481 |
| Protein Name | Insulin-like growth factor II |
| Description of Target | The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464). |
| Uniprot ID | P01344 |
| Protein Size (# AA) | Partial |
| Molecular Weight | 44.1 kda |
