Semaglutide [910463-68-2]
Referentie NB-64-09680-1mg
Formaat : 1mg
Merk : Neo Biotech
Semaglutide
Catalog No. T19850 Copy Product Info
Purity: 99.78%
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
Semaglutide
Copy Product InfoSemaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
Cas No. 910463-68-2
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor). |
| Targets&IC50 | albumin:27 µM, GLP1 receptor:6.2 pM (EC50) |
| Molecular Weight | 4114 |
| Formula | C187H291N45O59 |
| Cas No. | 910463-68-2 |
| Smiles | CC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(C(C)(NC([C@@H](N)CC1=CN=CN1)=O)C)=O)CCC(O)=O)=O)=O)[C@H](O)C)=O)CC2=CC=CC=C2)=O)[C@H](O)C)=O)CO)=O)CC(O)=O)=O)C(C)C)=O)CO)=O)CO)=O)CC3=CC=C(O)C=C3)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@@H](NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)=O)CCC(O)=O)=O)CC4=CC=CC=C4)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(O)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(C)C)=O)CC5=CNC6=CC=CC=C65)=O)C)=O)C |
| Relative Density. | no data available |
| Sequence | His-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-{C18 diacid-γ-Glu-(AEEA)2-Lys}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly |
| Sequence Short | {Aib}-EGTFTSDVSSYLEGQAA-{C18 diacid-γ-Glu-(AEEA)2-Lys}-EFIAWLVRGRG |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: 10 mg/mL (2.43 mM), when pH is adjusted to 14 with NaOH. Sonication and heating are recommended.  H2O: insoluble DMSO: 50 mg/mL (12.15 mM), Sonication is recommended. H2O: 5 mg/mL (1.22 mM), when pH is adjusted to 1 with HCl. Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O/H2O/DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||
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