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> SRC pTyr416 Mouse Monoclonal Antibody [Clone ID: 9A6]

SRC pTyr416 Mouse Monoclonal Antibody [Clone ID: 9A6]

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Referentie AM00145BT-N

Formaat : 100ug


SRC pTyr416 Mouse Monoclonal Antibody [Clone ID: 9A6]

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SKU
AM00145BT-N
SRC pTyr416 mouse monoclonal antibody, clone 9A6, Biotin
Size:
100 ug
Conjugation:
Biotin Unconjugated
 

View other "SRC or NP_005408.1" antibodies

Specifications
Product Data
Clone Name 9A6
Application ELISA, FC, IF, WB
Recommended Dilution Western Blot: 0.5 µg/ml for HRPO/ECL detection.
Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer.
ELISA: 0.05 µg/ml.
Flow Cytometry.
Immunocytochemistry.
Reactivity Human, Mouse
Antibody Host Mouse
Isotype IgG3
Clonality Monoclonal
Immunogen Synthetic phosphopeptide conjuagted to KLH
Specificity This antibody specifically interacts with activated src phosphorylated at Tyr 416 and with src family kinases phosphorylated at the corresponding Tyr in the activation loop. The antibody does not crossreact with the non-phosphorylated form of src nor with unrelated phosphorylation sites.
Buffer 0.5 mg/ml in PBS/0.09% Na-Azide/PEG and Sucrose.
Label: Biotin
State: Liquid purified IgG fraction.
Purification Subsequent Thiophilic Adsorption and Size Exclusion Chromatography
Conjugation Biotin
Storage Store the antibody (Aliquote and freeze in liquid nitrogen)at -80°C.
Avoid repeated freezing and thawing.
Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name SRC proto-oncogene, non-receptor tyrosine kinase
Database Link
Background Src is the best understood member of a family of nine tyrosine kinases regulating cellular responses to extracellular stimuli. Src becomes activated upon dephosphorylation of Tyr 527, leading to a conformational change of the src molecule towards an open, active conformation which allows binding to other proteins via the SH2 and SH3 domain. Activated src phosphorylates a variety of substrates involved in the mitogenic signalling pathway, cytoskeletal organization, cell-substrate adhesion, cell-cell adhesion, cell-cell communication, and RNA processing.
Synonyms c-Src, pp60c-src
Note Molecular weight of antigen: 60 kDa
Reference Data
Protein Categories Cardiovascular diseases, Cytokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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